Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdhD_2Dihydrolipoyl dehydrogenase. (461 aa)    
Predicted Functional Partners:
pdhC_5
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 0.941
pdhC_3
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 0.899
pdhC_2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 0.893
pdhC_4
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 0.890
pdhC_1
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.888
gcvPB_2
Putative glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
  
 0.762
gcvT_3
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 0.757
odhB_1
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex.
  
 0.753
acoA_2
Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha.
  
 
 0.731
acoA_4
Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha.
  
 
 0.731
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.