cobB_2 protein (Acetobacterium wieringae) - STRING interaction network

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cobB_2

NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (242 aa)

Predicted Functional Partners:

nadE

0.943

nadD

0.928

nadK

0.916

ACWI_23920

0.818

cdaR_2

0.808

recQ

0.722

uvrD2

0.722

ACWI_02290

0.710

ACWI_17910

0.686

gdhA

0.674

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACWI_02290	cobB_2	ACWI_02290	ACWI_17900	Hypothetical protein; TfoX N-terminal domain.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.710
ACWI_17910	cdaR_2	ACWI_17910	ACWI_17890	Dienelactone hydrolase family protein.	Carbohydrate diacid regulator.	0.692
ACWI_17910	cobB_2	ACWI_17910	ACWI_17900	Dienelactone hydrolase family protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.686
ACWI_17910	nadK	ACWI_17910	ACWI_11800	Dienelactone hydrolase family protein.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.603
ACWI_23920	cobB_2	ACWI_23920	ACWI_17900	Hypothetical protein.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.818
cdaR_2	ACWI_17910	ACWI_17890	ACWI_17910	Carbohydrate diacid regulator.	Dienelactone hydrolase family protein.	0.692
cdaR_2	cobB_2	ACWI_17890	ACWI_17900	Carbohydrate diacid regulator.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.808
cobB_2	ACWI_02290	ACWI_17900	ACWI_02290	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Hypothetical protein; TfoX N-terminal domain.	0.710
cobB_2	ACWI_17910	ACWI_17900	ACWI_17910	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Dienelactone hydrolase family protein.	0.686
cobB_2	ACWI_23920	ACWI_17900	ACWI_23920	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Hypothetical protein.	0.818
cobB_2	cdaR_2	ACWI_17900	ACWI_17890	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Carbohydrate diacid regulator.	0.808
cobB_2	gdhA	ACWI_17900	ACWI_02550	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.674
cobB_2	nadD	ACWI_17900	ACWI_21490	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.928
cobB_2	nadE	ACWI_17900	ACWI_01190	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.943
cobB_2	nadK	ACWI_17900	ACWI_11800	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.916
cobB_2	recQ	ACWI_17900	ACWI_04880	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	ATP-dependent DNA helicase RecQ.	0.722
cobB_2	uvrD2	ACWI_17900	ACWI_30560	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	ATP-dependent DNA helicase UvrD2.	0.722
gdhA	cobB_2	ACWI_02550	ACWI_17900	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.674
gdhA	nadE	ACWI_02550	ACWI_01190	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.571
nadD	cobB_2	ACWI_21490	ACWI_17900	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.928

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