| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACWI_18940 | apt | ACWI_18940 | ACWI_18910 | Putative metallo-hydrolase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.646 |
| ACWI_18940 | aspS | ACWI_18940 | ACWI_18960 | Putative metallo-hydrolase. | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.575 |
| ACWI_18940 | dtd | ACWI_18940 | ACWI_18930 | Putative metallo-hydrolase. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.726 |
| ACWI_18940 | hemZ | ACWI_18940 | ACWI_18950 | Putative metallo-hydrolase. | Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ. | 0.820 |
| ACWI_18940 | recJ | ACWI_18940 | ACWI_18900 | Putative metallo-hydrolase. | single-stranded-DNA-specific exonuclease RecJ. | 0.612 |
| ACWI_18940 | relA_1 | ACWI_18940 | ACWI_10460 | Putative metallo-hydrolase. | GTP pyrophosphokinase. | 0.400 |
| ACWI_18940 | relA_2 | ACWI_18940 | ACWI_18920 | Putative metallo-hydrolase. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.802 |
| ACWI_18940 | relA_3 | ACWI_18940 | ACWI_19370 | Putative metallo-hydrolase. | Bifunctional (p)ppGpp synthase/hydrolase RelA. | 0.412 |
| ACWI_18940 | secD | ACWI_18940 | ACWI_18880 | Putative metallo-hydrolase. | Protein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.533 |
| ACWI_18940 | secF | ACWI_18940 | ACWI_18890 | Putative metallo-hydrolase. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.448 |
| apt | ACWI_18940 | ACWI_18910 | ACWI_18940 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative metallo-hydrolase. | 0.646 |
| apt | aspS | ACWI_18910 | ACWI_18960 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.578 |
| apt | dtd | ACWI_18910 | ACWI_18930 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.771 |
| apt | hemZ | ACWI_18910 | ACWI_18950 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ. | 0.734 |
| apt | recJ | ACWI_18910 | ACWI_18900 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | single-stranded-DNA-specific exonuclease RecJ. | 0.815 |
| apt | relA_2 | ACWI_18910 | ACWI_18920 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.730 |
| apt | secD | ACWI_18910 | ACWI_18880 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Protein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.693 |
| apt | secF | ACWI_18910 | ACWI_18890 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.621 |
| aspS | ACWI_18940 | ACWI_18960 | ACWI_18940 | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Putative metallo-hydrolase. | 0.575 |
| aspS | apt | ACWI_18960 | ACWI_18910 | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.578 |
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