gshAB_2 protein (Acetobacterium wieringae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

gshAB_2

Glutathione biosynthesis bifunctional protein GshAB. (329 aa)

Predicted Functional Partners:

pksJ

0.901

gshAB_1

0.884

glnA_1

0.838

murC

0.828

sucD

0.811

mccB

0.805

metB

0.805

lgrD

0.798

ACWI_28430

0.788

sfrB_3

0.774

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACWI_28430	gshAB_1	ACWI_28430	ACWI_18380	Ureidoglycolate lyase.	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	0.788
ACWI_28430	gshAB_2	ACWI_28430	ACWI_20280	Ureidoglycolate lyase.	Glutathione biosynthesis bifunctional protein GshAB.	0.788
ACWI_28430	pksJ	ACWI_28430	ACWI_26840	Ureidoglycolate lyase.	Polyketide synthase PksJ.	0.772
ACWI_28430	sfrB_3	ACWI_28430	ACWI_30690	Ureidoglycolate lyase.	NADPH-Fe(3+) oxidoreductase subunit beta.	0.565
ACWI_28430	sucD	ACWI_28430	ACWI_25680	Ureidoglycolate lyase.	Succinate-semialdehyde dehydrogenase (acetylating).	0.685
glnA_1	gshAB_1	ACWI_23840	ACWI_18380	Glutamine synthetase.	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	0.838
glnA_1	gshAB_2	ACWI_23840	ACWI_20280	Glutamine synthetase.	Glutathione biosynthesis bifunctional protein GshAB.	0.838
glnA_1	pksJ	ACWI_23840	ACWI_26840	Glutamine synthetase.	Polyketide synthase PksJ.	0.921
glnA_1	sfrB_3	ACWI_23840	ACWI_30690	Glutamine synthetase.	NADPH-Fe(3+) oxidoreductase subunit beta.	0.827
glnA_1	sucD	ACWI_23840	ACWI_25680	Glutamine synthetase.	Succinate-semialdehyde dehydrogenase (acetylating).	0.700
gshAB_1	ACWI_28430	ACWI_18380	ACWI_28430	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	Ureidoglycolate lyase.	0.788
gshAB_1	glnA_1	ACWI_18380	ACWI_23840	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	Glutamine synthetase.	0.838
gshAB_1	gshAB_2	ACWI_18380	ACWI_20280	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	Glutathione biosynthesis bifunctional protein GshAB.	0.884
gshAB_1	lgrD	ACWI_18380	ACWI_30370	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	Linear gramicidin synthase subunit D; Belongs to the ATP-dependent AMP-binding enzyme family.	0.798
gshAB_1	mccB	ACWI_18380	ACWI_27030	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	Cystathionine gamma-lyase.	0.805
gshAB_1	metB	ACWI_18380	ACWI_27070	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	Cystathionine gamma-synthase.	0.805
gshAB_1	murC	ACWI_18380	ACWI_01490	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	0.828
gshAB_1	pksJ	ACWI_18380	ACWI_26840	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	Polyketide synthase PksJ.	0.901
gshAB_1	sfrB_3	ACWI_18380	ACWI_30690	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	NADPH-Fe(3+) oxidoreductase subunit beta.	0.774
gshAB_1	sucD	ACWI_18380	ACWI_25680	Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.	Succinate-semialdehyde dehydrogenase (acetylating).	0.811