purB protein (Acetobacterium wieringae) - STRING interaction network

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purB

Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (477 aa)

Predicted Functional Partners:

purC

0.999

purA

0.998

purH

0.996

purL

0.996

purK

0.994

purF

0.993

purM

0.989

purD

0.988

apt

0.980

purE_1

0.976

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
apt	purA	ACWI_18910	ACWI_23780	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.812
apt	purB	ACWI_18910	ACWI_20640	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.980
apt	purC	ACWI_18910	ACWI_28190	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.	0.511
apt	purD	ACWI_18910	ACWI_28140	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Phosphoribosylamine--glycine ligase; Belongs to the GARS family.	0.557
apt	purE_1	ACWI_18910	ACWI_23790	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.524
apt	purF	ACWI_18910	ACWI_28180	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.	0.602
apt	purH	ACWI_18910	ACWI_28150	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Bifunctional purine biosynthesis protein PurH.	0.970
apt	purK	ACWI_18910	ACWI_23810	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.638
apt	purL	ACWI_18910	ACWI_28210	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Phosphoribosylformylglycinamidine synthase.	0.823
apt	purM	ACWI_18910	ACWI_28170	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Phosphoribosylformylglycinamidine cyclo-ligase.	0.637
purA	apt	ACWI_23780	ACWI_18910	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.812
purA	purB	ACWI_23780	ACWI_20640	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.998
purA	purC	ACWI_23780	ACWI_28190	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.	0.974
purA	purD	ACWI_23780	ACWI_28140	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Phosphoribosylamine--glycine ligase; Belongs to the GARS family.	0.875
purA	purE_1	ACWI_23780	ACWI_23790	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.963
purA	purF	ACWI_23780	ACWI_28180	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.	0.815
purA	purH	ACWI_23780	ACWI_28150	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Bifunctional purine biosynthesis protein PurH.	0.986
purA	purK	ACWI_23780	ACWI_23810	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.977
purA	purL	ACWI_23780	ACWI_28210	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Phosphoribosylformylglycinamidine synthase.	0.967
purA	purM	ACWI_23780	ACWI_28170	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Phosphoribosylformylglycinamidine cyclo-ligase.	0.750