Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arsA_3Arsenical pump-driving ATPase. (571 aa)    
Predicted Functional Partners:
arsD_2
Arsenical resistance operon trans-acting repressor ArsD.
   
 0.972
arsA_2
Arsenical pump-driving ATPase.
 
  
0.934
arsA_1
Arsenical pump-driving ATPase.
  
  
 
0.927
arsD_3
Arsenical resistance operon trans-acting repressor ArsD.
 
   
 0.806
arsD_1
Arsenical resistance operon trans-acting repressor ArsD.
 
   
 0.804
arsC_1
Glutaredoxin arsenate reductase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
    
 0.742
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
    
 
 0.737
ftsH_2
ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family.
  
 
 0.659
ACWI_07100
Hypothetical protein.
  
 
 0.635
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
    
 
 0.625
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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