Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
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[Homology]
Score
fprANitric oxide reductase. (396 aa)    
Predicted Functional Partners:
hrb
High molecular weight rubredoxin.
  
 0.933
nasB
Assimilatory nitrate reductase electron transfer subunit.
 
  
 0.927
mnmA_2
tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.631
rbr1
Rubrerythrin-1.
 
  
 0.582
dfx_3
Desulfoferrodoxin.
 
  
 0.556
ACWI_21980
Bacteriohemerythrin.
  
  
 0.552
ACWI_30040
Bacteriohemerythrin.
  
  
 0.552
ngr
Nigerythrin.
 
  
 0.513
ACWI_18020
Rubredoxin.
 
  
 0.496
dfx_2
Desulfoferrodoxin.
  
  
 0.481
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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