Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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thiC_1Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (437 aa)    
Predicted Functional Partners:
thiD
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
 
 0.978
thiE
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.966
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 0.874
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
     
 0.810
thiH_2
2-iminoacetate synthase.
  
 0.784
thiS
Sulfur carrier protein ThiS.
  
  
 0.770
thiH_1
2-iminoacetate synthase.
  
  
 0.678
tenI
Regulatory protein TenI.
  
  
 0.677
moeB_1
Molybdopterin-synthase adenylyltransferase.
  
  
 0.622
moeB_2
Molybdopterin-synthase adenylyltransferase.
  
  
 0.622
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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