Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cymR_2HTH-type transcriptional regulator CymR. (144 aa)    
Predicted Functional Partners:
ACWI_25020
MOSC domain protein.
     
 0.626
iscS_1
Cysteine desulfurase IscS.
  
  
 0.614
iscS_2
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
  
 0.614
iscS_3
Cysteine desulfurase IscS.
  
  
 0.614
iscS_4
Cysteine desulfurase IscS.
  
  
 0.614
fliG
Flagellar motor switch protein FliG.
    
   0.527
iscU_1
Iron-sulfur cluster assembly scaffold protein IscU.
  
  
 0.469
iscU_2
Iron-sulfur cluster assembly scaffold protein IscU.
  
  
 0.469
ACWI_31780
Dinitrogenase iron-molybdenum cofactor.
  
  
 0.469
ACWI_02120
Hypothetical protein.
  
  
 0.462
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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