Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
addBATP-dependent helicase/deoxyribonuclease subunit B; ATP-dependent DNA helicase. (1116 aa)    
Predicted Functional Partners:
addA
ATP-dependent helicase/nuclease subunit A; ATP-dependent DNA helicase.
 
 
 0.999
sbcD
Nuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.694
trmK
tRNA (adenine(22)-N(1))-methyltransferase.
 
     0.656
ACWI_08320
Putative GTP cyclohydrolase 1 type 2; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
 
     0.542
sbcC
Nuclease SbcCD subunit C.
 
  
 0.536
trpS
tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.528
yhaM
3'-5' exoribonuclease YhaM.
 
     0.477
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
  
    0.477
yjbM
GTP pyrophosphokinase YjbM.
  
     0.472
smc_2
Chromosome partition protein Smc.
       0.461
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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