| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACWI_11780 | ACWI_25980 | ACWI_11780 | ACWI_25980 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Putative zinc metalloprotease. | 0.679 |
| ACWI_11780 | cdsA | ACWI_11780 | ACWI_25970 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.419 |
| ACWI_11780 | dxr | ACWI_11780 | ACWI_26030 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.546 |
| ACWI_11780 | ispG | ACWI_11780 | ACWI_25990 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.443 |
| ACWI_11780 | rsmB | ACWI_11780 | ACWI_19130 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.648 |
| ACWI_11780 | topA | ACWI_11780 | ACWI_29460 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.563 |
| ACWI_11780 | uppS | ACWI_11780 | ACWI_25960 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Isoprenyl transferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.973 |
| ACWI_25980 | ACWI_11780 | ACWI_25980 | ACWI_11780 | Putative zinc metalloprotease. | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.679 |
| ACWI_25980 | cdsA | ACWI_25980 | ACWI_25970 | Putative zinc metalloprotease. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.930 |
| ACWI_25980 | dxr | ACWI_25980 | ACWI_26030 | Putative zinc metalloprotease. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.695 |
| ACWI_25980 | ispG | ACWI_25980 | ACWI_25990 | Putative zinc metalloprotease. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.790 |
| ACWI_25980 | polC_2 | ACWI_25980 | ACWI_26000 | Putative zinc metalloprotease. | DNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.784 |
| ACWI_25980 | rsmB | ACWI_25980 | ACWI_19130 | Putative zinc metalloprotease. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.696 |
| ACWI_25980 | spoIIIE | ACWI_25980 | ACWI_29280 | Putative zinc metalloprotease. | DNA translocase SpoIIIE. | 0.659 |
| ACWI_25980 | spoVD | ACWI_25980 | ACWI_17800 | Putative zinc metalloprotease. | Stage V sporulation protein D. | 0.663 |
| ACWI_25980 | topA | ACWI_25980 | ACWI_29460 | Putative zinc metalloprotease. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.761 |
| ACWI_25980 | uppS | ACWI_25980 | ACWI_25960 | Putative zinc metalloprotease. | Isoprenyl transferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.948 |
| cdsA | ACWI_11780 | ACWI_25970 | ACWI_11780 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.419 |
| cdsA | ACWI_25980 | ACWI_25970 | ACWI_25980 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Putative zinc metalloprotease. | 0.930 |
| cdsA | dxr | ACWI_25970 | ACWI_26030 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.759 |