Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tcdA_2tRNA threonylcarbamoyladenosine dehydratase. (261 aa)    
Predicted Functional Partners:
ttcA_2
tRNA 2-thiocytidine biosynthesis protein TtcA; Belongs to the TtcA family.
  
 
 0.721
cysK_3
Cysteine synthase.
   
 
 0.614
iscS_4
Cysteine desulfurase IscS.
     
 0.604
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.556
yvbK
Putative N-acetyltransferase YvbK.
   
    0.520
moeB_2
Molybdopterin-synthase adenylyltransferase.
 
 
0.485
moeB_1
Molybdopterin-synthase adenylyltransferase.
 
 
0.444
cysK_1
Cysteine synthase.
    
 
 0.435
cysK_2
Cysteine synthase.
    
 
 0.435
mccA
O-acetylserine dependent cystathionine beta-synthase.
    
 
 0.435
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.