Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemE_7Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (384 aa)    
Predicted Functional Partners:
hemE_1
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
 
     0.769
hemE_3
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
 
     0.768
ACWI_32780
Methylcobalamin:coenzyme M methyltransferase; Belongs to the uroporphyrinogen decarboxylase family.
  
     0.768
metH_17
Methionine synthase.
 
    0.763
ACWI_34950
Methylcobalamin:coenzyme M methyltransferase; Belongs to the uroporphyrinogen decarboxylase family.
  
     0.762
ACWI_04090
Methylcobalamin:coenzyme M methyltransferase; Belongs to the uroporphyrinogen decarboxylase family.
  
     0.760
hemE_6
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
 
     0.754
ACWI_34800
Methylcobalamin:coenzyme M methyltransferase; Belongs to the uroporphyrinogen decarboxylase family.
  
     0.751
ACWI_32760
Methylcobalamin:coenzyme M methyltransferase; Belongs to the uroporphyrinogen decarboxylase family.
  
     0.748
nasF
uroporphyrinogen-III C-methyltransferase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 
 0.725
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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