ACWI_28000 protein (Acetobacterium wieringae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ACWI_28000

Cobalt-dependent inorganic pyrophosphatase. (540 aa)

Predicted Functional Partners:

atpD_2

0.916

atpB

0.910

atpC_2

0.908

atpG

0.908

atpH_2

0.908

atpF_2

0.908

atpE_2

0.908

atpE_4

0.908

atpH_1

0.906

atpA_2

0.906

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACWI_28000	atpA_2	ACWI_28000	ACWI_23450	Cobalt-dependent inorganic pyrophosphatase.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	0.906
ACWI_28000	atpB	ACWI_28000	ACWI_23510	Cobalt-dependent inorganic pyrophosphatase.	ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.	0.910
ACWI_28000	atpC_2	ACWI_28000	ACWI_23420	Cobalt-dependent inorganic pyrophosphatase.	ATP synthase epsilon chain, sodium ion specific; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.908
ACWI_28000	atpD_2	ACWI_28000	ACWI_23430	Cobalt-dependent inorganic pyrophosphatase.	ATP synthase subunit beta, sodium ion specific; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.	0.916
ACWI_28000	atpE_2	ACWI_28000	ACWI_23480	Cobalt-dependent inorganic pyrophosphatase.	ATP synthase subunit c, sodium ion specific; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	0.908
ACWI_28000	atpE_4	ACWI_28000	ACWI_23500	Cobalt-dependent inorganic pyrophosphatase.	ATP synthase subunit c, sodium ion specific; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	0.908
ACWI_28000	atpF_2	ACWI_28000	ACWI_23470	Cobalt-dependent inorganic pyrophosphatase.	ATP synthase subunit b, sodium ion specific; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.	0.908
ACWI_28000	atpG	ACWI_28000	ACWI_23440	Cobalt-dependent inorganic pyrophosphatase.	ATP synthase gamma chain, sodium ion specific; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.	0.908
ACWI_28000	atpH_1	ACWI_28000	ACWI_03850	Cobalt-dependent inorganic pyrophosphatase.	ATP synthase subunit c; Belongs to the V-ATPase proteolipid subunit family.	0.906
ACWI_28000	atpH_2	ACWI_28000	ACWI_23460	Cobalt-dependent inorganic pyrophosphatase.	ATP synthase subunit delta, sodium ion specific; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	0.908
atpA_2	ACWI_28000	ACWI_23450	ACWI_28000	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	Cobalt-dependent inorganic pyrophosphatase.	0.906
atpA_2	atpB	ACWI_23450	ACWI_23510	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.	0.999
atpA_2	atpC_2	ACWI_23450	ACWI_23420	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	ATP synthase epsilon chain, sodium ion specific; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
atpA_2	atpD_2	ACWI_23450	ACWI_23430	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	ATP synthase subunit beta, sodium ion specific; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.	0.999
atpA_2	atpE_2	ACWI_23450	ACWI_23480	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	ATP synthase subunit c, sodium ion specific; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	0.999
atpA_2	atpE_4	ACWI_23450	ACWI_23500	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	ATP synthase subunit c, sodium ion specific; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	0.998
atpA_2	atpF_2	ACWI_23450	ACWI_23470	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	ATP synthase subunit b, sodium ion specific; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.	0.999
atpA_2	atpG	ACWI_23450	ACWI_23440	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	ATP synthase gamma chain, sodium ion specific; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.	0.999
atpA_2	atpH_1	ACWI_23450	ACWI_03850	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	ATP synthase subunit c; Belongs to the V-ATPase proteolipid subunit family.	0.954
atpA_2	atpH_2	ACWI_23450	ACWI_23460	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	ATP synthase subunit delta, sodium ion specific; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	0.999