STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ACWI_29490Putative universal stress protein. (288 aa)    
Predicted Functional Partners:
teaD
TRAP-T-associated universal stress protein TeaD.
  
     0.736
ogt
methylated-DNA--protein-cysteine methyltransferase, constitutive; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.632
fliY_2
Cystine-binding periplasmic protein precursor; Belongs to the bacterial solute-binding protein 3 family.
  
 
 0.581
ACWI_15650
Hypothetical protein.
  
  
 0.572
ACWI_34470
B12 binding domain protein.
  
     0.550
barA_1
Signal transduction histidine-protein kinase BarA.
  
 
 0.539
ACWI_29500
Hypothetical protein.
       0.536
prkC_1
Serine/threonine-protein kinase PrkC.
  
  
 0.533
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.532
ACWI_29510
Hypothetical protein.
       0.499
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.