Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rtcBRNA-splicing ligase RtcB. (357 aa)    
Predicted Functional Partners:
ACWI_33130
Hypothetical protein.
       0.762
ACWI_33140
Hypothetical protein.
       0.762
cshA
DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family.
   
 0.685
rhlE
ATP-dependent RNA helicase RhlE.
   
 0.685
dbpA_2
ATP-dependent RNA helicase DbpA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.
   
 0.685
ACWI_15650
Hypothetical protein.
  
  
 0.639
cdr_1
Coenzyme A disulfide reductase.
   
 
 0.502
cdr_2
Coenzyme A disulfide reductase.
   
 
 0.502
cdr_3
Coenzyme A disulfide reductase.
   
 
 0.502
cdr_4
Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family.
   
 
 0.502
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
Server load: low (8%) [HD]