Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACWI_33640Collagen triple helix repeat (20 copies). (556 aa)    
Predicted Functional Partners:
ACWI_33630
Kelch motif protein.
 
     0.897
ACWI_33660
Prophage endopeptidase tail.
   
   0.861
spoIIIE
DNA translocase SpoIIIE.
    
 
 0.732
ACWI_33650
Hypothetical protein.
       0.727
ACWI_33680
Tropomyosin like protein.
       0.709
pksJ
Polyketide synthase PksJ.
  
 
 0.701
ACWI_33670
Hypothetical protein.
       0.688
ACWI_03700
Hypothetical protein.
    
   0.660
ACWI_32930
Hypothetical protein.
    
   0.660
ACWI_22120
Hypothetical protein.
    
 
 0.650
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
Server load: low (26%) [HD]