dmg protein (Acetobacterium wieringae) - STRING interaction network

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dmg

Dimethylglycine oxidase; Belongs to the GcvT family. (458 aa)

Predicted Functional Partners:

gcvH_3

0.845

gcvH_1

0.844

gcvH_2

0.844

gcvPB_1

0.795

gcvPB_2

0.795

mlr

0.784

lpd_4

0.675

gcvPA_1

0.643

gcvPA_2

0.643

glyA

0.618

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dmg	gcvH_1	ACWI_34820	ACWI_02630	Dimethylglycine oxidase; Belongs to the GcvT family.	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.844
dmg	gcvH_2	ACWI_34820	ACWI_16410	Dimethylglycine oxidase; Belongs to the GcvT family.	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.844
dmg	gcvH_3	ACWI_34820	ACWI_21120	Dimethylglycine oxidase; Belongs to the GcvT family.	Glycine cleavage system H protein.	0.845
dmg	gcvPA_1	ACWI_34820	ACWI_02610	Dimethylglycine oxidase; Belongs to the GcvT family.	Putative glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.643
dmg	gcvPA_2	ACWI_34820	ACWI_16420	Dimethylglycine oxidase; Belongs to the GcvT family.	Putative glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.643
dmg	gcvPB_1	ACWI_34820	ACWI_02600	Dimethylglycine oxidase; Belongs to the GcvT family.	Putative glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.795
dmg	gcvPB_2	ACWI_34820	ACWI_16430	Dimethylglycine oxidase; Belongs to the GcvT family.	Putative glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.795
dmg	glyA	ACWI_34820	ACWI_35470	Dimethylglycine oxidase; Belongs to the GcvT family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.618
dmg	lpd_4	ACWI_34820	ACWI_24190	Dimethylglycine oxidase; Belongs to the GcvT family.	Dihydrolipoyl dehydrogenase.	0.675
dmg	mlr	ACWI_34820	ACWI_28760	Dimethylglycine oxidase; Belongs to the GcvT family.	4-methylaminobutanoate oxidase (formaldehyde-forming).	0.784
gcvH_1	dmg	ACWI_02630	ACWI_34820	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Dimethylglycine oxidase; Belongs to the GcvT family.	0.844
gcvH_1	gcvH_2	ACWI_02630	ACWI_16410	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.404
gcvH_1	gcvH_3	ACWI_02630	ACWI_21120	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Glycine cleavage system H protein.	0.911
gcvH_1	gcvPA_1	ACWI_02630	ACWI_02610	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Putative glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.997
gcvH_1	gcvPA_2	ACWI_02630	ACWI_16420	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Putative glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.929
gcvH_1	gcvPB_1	ACWI_02630	ACWI_02600	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Putative glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.999
gcvH_1	gcvPB_2	ACWI_02630	ACWI_16430	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Putative glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.984
gcvH_1	glyA	ACWI_02630	ACWI_35470	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.963
gcvH_1	lpd_4	ACWI_02630	ACWI_24190	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Dihydrolipoyl dehydrogenase.	0.991
gcvH_2	dmg	ACWI_16410	ACWI_34820	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Dimethylglycine oxidase; Belongs to the GcvT family.	0.844