STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACWI_35110GMP synthase subunit B. (271 aa)    
Predicted Functional Partners:
larB
AIR carboxylase.
  
 0.934
ACWI_14360
AIR carboxylase.
  
 0.932
larC
Hypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
  
 0.928
ACWI_14370
Hypothetical protein.
  
 0.907
ACWI_11280
Hypothetical protein.
 
  
 0.776
ACWI_15200
Hypothetical protein.
 
  
 0.776
ykoC
Putative HMP/thiamine permease protein YkoC.
  
    0.638
cbiM_1
Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.562
cbiM_2
Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.562
nikMN
Fused nickel transport protein NikMN.
  
    0.562
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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