thiC_2 protein (Acetobacterium wieringae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

thiC_2

Phosphomethylpyrimidine synthase. (435 aa)

Predicted Functional Partners:

thiC_3

0.978

prmB

0.944

thiE

0.939

ACWI_02830

0.904

thiD

0.880

thiG

0.844

thiS

0.770

thiH_2

0.723

thiH_1

0.678

tenI

0.677

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACWI_02830	prmB	ACWI_02830	ACWI_35180	Hypothetical protein.	50S ribosomal protein L3 glutamine methyltransferase.	0.919
ACWI_02830	thiC_2	ACWI_02830	ACWI_35150	Hypothetical protein.	Phosphomethylpyrimidine synthase.	0.904
ACWI_02830	thiC_3	ACWI_02830	ACWI_35160	Hypothetical protein.	Phosphomethylpyrimidine synthase.	0.904
prmB	ACWI_02830	ACWI_35180	ACWI_02830	50S ribosomal protein L3 glutamine methyltransferase.	Hypothetical protein.	0.919
prmB	thiC_2	ACWI_35180	ACWI_35150	50S ribosomal protein L3 glutamine methyltransferase.	Phosphomethylpyrimidine synthase.	0.944
prmB	thiC_3	ACWI_35180	ACWI_35160	50S ribosomal protein L3 glutamine methyltransferase.	Phosphomethylpyrimidine synthase.	0.944
tenI	thiC_2	ACWI_12910	ACWI_35150	Regulatory protein TenI.	Phosphomethylpyrimidine synthase.	0.677
tenI	thiC_3	ACWI_12910	ACWI_35160	Regulatory protein TenI.	Phosphomethylpyrimidine synthase.	0.677
tenI	thiD	ACWI_12910	ACWI_15970	Regulatory protein TenI.	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.	0.998
tenI	thiE	ACWI_12910	ACWI_15950	Regulatory protein TenI.	Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.930
tenI	thiG	ACWI_12910	ACWI_12930	Regulatory protein TenI.	Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.969
tenI	thiH_1	ACWI_12910	ACWI_06160	Regulatory protein TenI.	2-iminoacetate synthase.	0.730
tenI	thiH_2	ACWI_12910	ACWI_12920	Regulatory protein TenI.	2-iminoacetate synthase.	0.913
tenI	thiS	ACWI_12910	ACWI_12940	Regulatory protein TenI.	Sulfur carrier protein ThiS.	0.915
thiC_2	ACWI_02830	ACWI_35150	ACWI_02830	Phosphomethylpyrimidine synthase.	Hypothetical protein.	0.904
thiC_2	prmB	ACWI_35150	ACWI_35180	Phosphomethylpyrimidine synthase.	50S ribosomal protein L3 glutamine methyltransferase.	0.944
thiC_2	tenI	ACWI_35150	ACWI_12910	Phosphomethylpyrimidine synthase.	Regulatory protein TenI.	0.677
thiC_2	thiC_3	ACWI_35150	ACWI_35160	Phosphomethylpyrimidine synthase.	Phosphomethylpyrimidine synthase.	0.978
thiC_2	thiD	ACWI_35150	ACWI_15970	Phosphomethylpyrimidine synthase.	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.	0.880
thiC_2	thiE	ACWI_35150	ACWI_15950	Phosphomethylpyrimidine synthase.	Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.939