Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
metH_27Methionine synthase. (226 aa)    
Predicted Functional Partners:
ACWI_35400
Trimethylamine methyltransferase (MTTB).
 
 
  0.983
ACWI_06320
Trimethylamine methyltransferase (MTTB).
  
 
  0.930
metH_6
Methionine synthase.
  
  
 
0.922
ACWI_06310
Trimethylamine methyltransferase (MTTB).
    
  0.919
ACWI_35410
Hypothetical protein.
 
     0.495
yurK
Putative HTH-type transcriptional regulator YurK.
 
     0.477
deoC1
Deoxyribose-phosphate aldolase 1; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
   
   0.469
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
   
   0.469
hemE_2
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
    0.436
ACWI_35450
Trimethylamine methyltransferase (MTTB).
 
 
   0.434
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
Server load: low (14%) [HD]