Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACWI_35600Stage II sporulation protein E (SpoIIE). (387 aa)    
Predicted Functional Partners:
ACWI_35620
Hypothetical protein.
 
    0.953
ACWI_35610
Iron hydrogenase 1.
 
     0.952
barA_2
Signal transduction histidine-protein kinase BarA.
  
  
 0.889
barA_1
Signal transduction histidine-protein kinase BarA.
  
  
 0.862
rsbT
Serine/threonine-protein kinase RsbT.
 
 
 0.810
btrV
Putative anti-sigma factor antagonist BtrV; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.798
ACWI_25800
Putative anti-sigma factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
 
 0.798
ACWI_14730
Hypothetical protein.
  
 
 0.698
rsbW
Serine-protein kinase RsbW.
  
 
 0.698
thiH_1
2-iminoacetate synthase.
  
    0.688
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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