Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACWI_35610Iron hydrogenase 1. (567 aa)    
Predicted Functional Partners:
ACWI_35620
Hypothetical protein.
 
 
 0.984
hndC_1
NADP-reducing hydrogenase subunit HndC.
 
 
 
 0.974
hndC_2
NADP-reducing hydrogenase subunit HndC.
 
 
 
 0.974
ACWI_35600
Stage II sporulation protein E (SpoIIE).
 
     0.952
ngr
Nigerythrin.
   
 
 0.924
sfrB_1
NADPH-Fe(3+) oxidoreductase subunit beta.
 
 
 0.922
sfrB_2
NADPH-Fe(3+) oxidoreductase subunit beta.
 
 
 0.922
hndD
NADP-reducing hydrogenase subunit HndC.
 
 
 
0.901
hndB
NADP-reducing hydrogenase subunit HndB.
 
 
 
 0.882
ACWI_24290
Ferredoxin, 2Fe-2S.
 
 
 
 0.871
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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