STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (420 aa)    
Predicted Functional Partners:
EEL51185.1
Similar to dihydroxy-acid dehydratase PRK00911; similar to Dihydroxy-acid dehydratase of cellular organisms UniRef RepID=ILVD_HELHP; Belongs to the IlvD/Edd family.
 
  
 0.919
EEL52202.1
Similar to glutamate synthase subunit alpha PRK11750; similar to Glutamate synthase, large subunit, putative of Bacillus cereus group UniRef RepID=Q81YV1_BACAN.
  
 
 0.899
EEL51186.1
Similar to dihydroxy-acid dehydratase PRK00911; similar to Dihydroxy-acid dehydratase of cellular organisms UniRef RepID=ILVD_THETN.
  
  
 0.891
EEL51005.1
Similar to homoserine dehydrogenase PRK06349; similar to homoserine dehydrogenase of Bacillus cereus W UniRef RepID=UPI00016B6978.
  
  
 0.864
EEL48321.1
Similar to homoserine dehydrogenase PRK06349; similar to Homoserine dehydrogenase of Bacilli UniRef RepID=DHOM_BACSU.
  
  
 0.864
EEL51493.1
Hypothetical protein; Similar to acetolactate synthase catalytic subunit PRK07710; similar to IlvB of cellular organisms UniRef RepID=A7Z7C1_BACA2.
 
 0.859
EEL51494.1
Similar to acetolactate synthase 3 regulatory subunit PRK11895; similar to Acetolactate synthase small subunit of Bacillales UniRef RepID=ILVH_BACSU.
 
 
 0.854
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
  
 0.775
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
  
 0.766
EEL51006.1
Similar to threonine synthase PRK06721; similar to Threonine synthase of cellular organisms UniRef RepID=THRC_BACSL.
  
 
0.753
Your Current Organism:
Bacillus cereus Rock344
NCBI taxonomy Id: 526986
Other names: B. cereus Rock3-44, Bacillus cereus Rock3-44
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