node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEL48340.1 | EEL50524.1 | bcere0022_43890 | bcere0022_21650 | Transcriptional regulator, TetR; Similar to Transcriptional regulator COG1309; similar to Transcriptional regulator, TetR family protein of Bacillales UniRef RepID=A6CQ36_9BACI. | Similar to Transcriptional regulator COG1309; similar to Transcriptional regulator TetR family of Bacillales UniRef RepID=A4IT56_GEOTN. | 0.443 |
EEL50524.1 | EEL48340.1 | bcere0022_21650 | bcere0022_43890 | Similar to Transcriptional regulator COG1309; similar to Transcriptional regulator TetR family of Bacillales UniRef RepID=A4IT56_GEOTN. | Transcriptional regulator, TetR; Similar to Transcriptional regulator COG1309; similar to Transcriptional regulator, TetR family protein of Bacillales UniRef RepID=A6CQ36_9BACI. | 0.443 |
EEL50524.1 | kynA | bcere0022_21650 | bcere0022_21620 | Similar to Transcriptional regulator COG1309; similar to Transcriptional regulator TetR family of Bacillales UniRef RepID=A4IT56_GEOTN. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.612 |
EEL50524.1 | kynB | bcere0022_21650 | bcere0022_21630 | Similar to Transcriptional regulator COG1309; similar to Transcriptional regulator TetR family of Bacillales UniRef RepID=A4IT56_GEOTN. | Metal-dependent hydrolase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.627 |
EEL50524.1 | kynU | bcere0022_21650 | bcere0022_21640 | Similar to Transcriptional regulator COG1309; similar to Transcriptional regulator TetR family of Bacillales UniRef RepID=A4IT56_GEOTN. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.588 |
kynA | EEL50524.1 | bcere0022_21620 | bcere0022_21650 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Similar to Transcriptional regulator COG1309; similar to Transcriptional regulator TetR family of Bacillales UniRef RepID=A4IT56_GEOTN. | 0.612 |
kynA | kynB | bcere0022_21620 | bcere0022_21630 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Metal-dependent hydrolase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.971 |
kynA | kynU | bcere0022_21620 | bcere0022_21640 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.977 |
kynB | EEL50524.1 | bcere0022_21630 | bcere0022_21650 | Metal-dependent hydrolase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | Similar to Transcriptional regulator COG1309; similar to Transcriptional regulator TetR family of Bacillales UniRef RepID=A4IT56_GEOTN. | 0.627 |
kynB | kynA | bcere0022_21630 | bcere0022_21620 | Metal-dependent hydrolase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.971 |
kynB | kynU | bcere0022_21630 | bcere0022_21640 | Metal-dependent hydrolase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.982 |
kynU | EEL50524.1 | bcere0022_21640 | bcere0022_21650 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Similar to Transcriptional regulator COG1309; similar to Transcriptional regulator TetR family of Bacillales UniRef RepID=A4IT56_GEOTN. | 0.588 |
kynU | kynA | bcere0022_21640 | bcere0022_21620 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.977 |
kynU | kynB | bcere0022_21640 | bcere0022_21630 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Metal-dependent hydrolase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.982 |