STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lexALexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (215 aa)    
Predicted Functional Partners:
EEL49751.1
Hypothetical protein; Similar to recombinase A PRK09354; similar to Protein recA of Eubacterium siraeum DSM 15702 UniRef RepID=B0MMT9_9FIRM.
  
 
 0.904
EEL49752.1
Endonuclease PI-MboI; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.
  
 
 0.904
dinB
Nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.768
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
  
  
 0.742
EEL49852.1
Resolvase; Similar to Site-specific recombinases, DNA invertase Pin homologs COG1961; similar to Resolvase, N-terminal domain of Firmicutes UniRef RepID=A8VVM2_9BACI.
  
  
 0.738
EEL49388.1
DNA repair protein recN; May be involved in recombinational repair of damaged DNA.
  
  
 0.686
EEL51688.1
Similar to anthranilate synthase component II PRK05670; similar to Anthranilate synthase component II of Bacteria UniRef RepID=A6CHN0_9BACI.
     
 0.666
cinA
Similar to competence damage-inducible protein A PRK00549; similar to Putative competence-damage inducible protein of Bacillus pumilus UniRef RepID=CINA_BACP2; Belongs to the CinA family.
     
 0.659
birA
Biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.657
EEL49176.1
Exonuclease RecJ; Similar to Single-stranded DNA-specific exonuclease COG0608; similar to Exonuclease RecJ of Bacillaceae UniRef RepID=A0RJ17_BACAH.
 
   
 0.649
Your Current Organism:
Bacillus cereus Rock344
NCBI taxonomy Id: 526986
Other names: B. cereus Rock3-44, Bacillus cereus Rock3-44
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