STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEL48529.1Similar to Integral membrane protein of Bacillus cereus group UniRef RepID=Q815J2_BACCR. (269 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.602
EEL48530.1
Similar to Thioredoxin reductase COG0492; similar to Thioredoxin reductase of Bacillus UniRef RepID=TRXB_BACSU.
       0.476
lutA-2
Glycolate oxidase; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
       0.468
mprF
Lysylcardiolipin synthase / Lysyltransferase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
       0.457
lutB-2
Uncharacterized electron transport protein ykgF; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate.
       0.447
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.444
EEL49825.1
Similar to 2-oxoglutarate ferredoxin oxidoreductase subunit alpha PRK08659; similar to Pyruvate ferredoxin oxidoreductase alpha chain of Bacillales UniRef RepID=Q2YXM8_STAAB.
       0.432
Your Current Organism:
Bacillus cereus Rock344
NCBI taxonomy Id: 526986
Other names: B. cereus Rock3-44, Bacillus cereus Rock3-44
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