STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAV94489.1Oxidoreductase, aldo/keto reductase family protein. (297 aa)    
Predicted Functional Partners:
GAV94673.1
Channel protein, MIP family; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.603
GAV95594.1
Hypothetical protein.
   
 0.602
GAV95595.1
Hypothetical protein.
   
 0.602
GAV95183.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.570
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.515
dnaJ
Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...]
    
   0.489
GAV94111.1
Chaperone DnaJ.
    
   0.489
GAV95352.1
Chaperone DnaJ.
    
   0.489
GAV94195.1
Organophosphate reductase.
 
 
0.460
GAV93402.1
Oxidoreductase, aldo/keto reductase family protein.
 
 
0.457
Your Current Organism:
Actinomyces denticolens
NCBI taxonomy Id: 52767
Other names: A. denticolens, ATCC 43322, CCUG 32758, CIP 103126, DSM 20671, NCTC 11490, strain Sh 8/4303
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