STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OKL52529.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family. (173 aa)    
Predicted Functional Partners:
OKL52635.1
Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
    
 0.780
OKL52200.1
NAD(+) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family.
  
 
 0.768
pdxT
Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.741
OKL52784.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.706
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.642
OKL52456.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.642
OKL51164.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.639
OKL52528.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.629
pdxS
Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
       0.627
OKL52463.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.626
Your Current Organism:
Actinomyces hordeovulneris
NCBI taxonomy Id: 52770
Other names: A. hordeovulneris, ATCC 35275, Actinomyces hordeivulneris, CCUG 32937, CIP 103149, DSM 20732, UCD 81-332-9
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.