STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadAQuinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (312 aa)    
Predicted Functional Partners:
APO43188.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
 0.999
APO43189.1
Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family.
 
 
 0.999
coaX
Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.797
APO47897.1
Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.753
hslO
Hsp33 family molecular chaperone; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
       0.747
APO43192.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.746
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
       0.723
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 0.711
APO43194.1
Anthranilate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.706
APO43198.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.701
Your Current Organism:
Paenibacillus xylanexedens
NCBI taxonomy Id: 528191
Other names: DSM 21292, NRRL B-51090, P. xylanexedens, Paenibacillus sp. B22a, Paenibacillus xylanexedens Nelson et al. 2009, strain B22a
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.