STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APO45104.1Alpha-xylosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 31 family. (772 aa)    
Predicted Functional Partners:
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
 
 0.788
APO45106.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.694
APO43787.1
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
 
 0.664
APO45105.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.639
APO45127.1
Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.613
APO43900.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.611
APO46518.1
Cellulase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.599
APO45103.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.586
APO45603.1
Cellulase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
  
 0.548
APO47242.1
Glycoside hydrolase 43 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 43 family.
 
   
 0.540
Your Current Organism:
Paenibacillus xylanexedens
NCBI taxonomy Id: 528191
Other names: DSM 21292, NRRL B-51090, P. xylanexedens, Paenibacillus sp. B22a, Paenibacillus xylanexedens Nelson et al. 2009, strain B22a
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