STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recARecombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (354 aa)    
Predicted Functional Partners:
recX
RecX family transcriptional regulator; Modulates RecA activity; Belongs to the RecX family.
  
 
 0.974
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
 0.968
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
 
 0.959
APO43318.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.940
APO47759.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.909
APO43703.1
DNA helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.887
APO44807.1
Flap endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.885
APO47911.1
ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.884
APO44563.1
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.867
cinA
Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
  
  
 0.861
Your Current Organism:
Paenibacillus xylanexedens
NCBI taxonomy Id: 528191
Other names: DSM 21292, NRRL B-51090, P. xylanexedens, Paenibacillus sp. B22a, Paenibacillus xylanexedens Nelson et al. 2009, strain B22a
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