STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALG70780.1NAD synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family. (555 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.958
ALG75483.1
ADP-ribose pyrophosphatase; NadM-Nudix subfamily; involved in creation of nicotanimide adenine dinucleotide NAD from either biosynthetic or salvage pathways; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.958
cobB
NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily.
   
 0.950
ppnK
Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.947
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
0.929
nadE-2
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
 
  
 0.928
ALG71688.1
NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.920
ALG73465.1
NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.920
ALG70564.1
NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.916
ALG71689.1
NAD(P) transhydrogenase subunit alpha part 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.905
Your Current Organism:
Azospirillum thiophilum
NCBI taxonomy Id: 528244
Other names: A. thiophilum, Azospirillum sp. BV-s, Azospirillum thiophilum Lavrinenko et al. 2010, DSM 21654, VKM B-2513, strain BV-S
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