A0A4S8IDR7 protein (Musa balbisiana) - STRING interaction network

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

A0A4S8IDR7

ENTH domain-containing protein. (642 aa)

Predicted Functional Partners:

A0A4S8JW58

0.742

A0A4S8JW63

0.742

A0A4S8KDI2

0.742

A0A4S8K3H3

0.714

A0A4S8KBB5

0.714

A0A4V4H8B7

0.714

A0A4S8JJK1

0.712

A0A4S8JKP0

0.712

A0A4S8K8P7

0.712

A0A4S8JS59

0.706

Your Current Organism:

Musa balbisiana

NCBI taxonomy Id: 52838
Other names: Balbis banana, M. balbisiana, Musa BB Group, Musa balbisiana Colla, starchy banana

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A4S8IDR7	A0A4S8JJK1	ENTH domain-containing protein.	Protein kinase domain-containing protein.	0.712
A0A4S8IDR7	A0A4S8JKP0	ENTH domain-containing protein.	Protein kinase domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	0.712
A0A4S8IDR7	A0A4S8JS59	ENTH domain-containing protein.	Clathrin-link domain-containing protein.	0.706
A0A4S8IDR7	A0A4S8JW58	ENTH domain-containing protein.	Adaptin_N domain-containing protein.	0.742
A0A4S8IDR7	A0A4S8JW63	ENTH domain-containing protein.	Uncharacterized protein.	0.742
A0A4S8IDR7	A0A4S8K3H3	ENTH domain-containing protein.	Uncharacterized protein.	0.714
A0A4S8IDR7	A0A4S8K8P7	ENTH domain-containing protein.	Protein kinase domain-containing protein.	0.712
A0A4S8IDR7	A0A4S8KBB5	ENTH domain-containing protein.	Uncharacterized protein.	0.714
A0A4S8IDR7	A0A4S8KDI2	ENTH domain-containing protein.	Alpha_adaptinC2 domain-containing protein.	0.742
A0A4S8IDR7	A0A4V4H8B7	ENTH domain-containing protein.	Uncharacterized protein.	0.714
A0A4S8JJK1	A0A4S8IDR7	Protein kinase domain-containing protein.	ENTH domain-containing protein.	0.712
A0A4S8JJK1	A0A4S8JS59	Protein kinase domain-containing protein.	Clathrin-link domain-containing protein.	0.748
A0A4S8JJK1	A0A4S8JW58	Protein kinase domain-containing protein.	Adaptin_N domain-containing protein.	0.819
A0A4S8JJK1	A0A4S8JW63	Protein kinase domain-containing protein.	Uncharacterized protein.	0.819
A0A4S8JJK1	A0A4S8K3H3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.880
A0A4S8JJK1	A0A4S8KBB5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.880
A0A4S8JJK1	A0A4S8KDI2	Protein kinase domain-containing protein.	Alpha_adaptinC2 domain-containing protein.	0.819
A0A4S8JJK1	A0A4V4H8B7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.880
A0A4S8JKP0	A0A4S8IDR7	Protein kinase domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	ENTH domain-containing protein.	0.712
A0A4S8JKP0	A0A4S8JS59	Protein kinase domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	Clathrin-link domain-containing protein.	0.748

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.889

expected number of edges:

13

PPI enrichment p-value:

6.25e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009132

Nucleoside diphosphate metabolic process

7 of 58

2.45

6.02

4.55e-13

GO:0072528

Pyrimidine-containing compound biosynthetic process

5 of 28

2.62

4.81

5.53e-10

GO:0009142

Nucleoside triphosphate biosynthetic process

5 of 29

2.6

4.78

6.02e-10

GO:0009141

Nucleoside triphosphate metabolic process

6 of 73

2.28

4.67

1.67e-10

GO:0090407

Organophosphate biosynthetic process

9 of 281

1.87

4.45

4.55e-13

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016776

Phosphotransferase activity, phosphate group as acceptor

6 of 25

2.74

6.13

1.82e-12

GO:0019205

Nucleobase-containing compound kinase activity

6 of 29

2.68

6.04

2.01e-12

GO:0004550

Nucleoside diphosphate kinase activity

3 of 4

3.24

3.23

1.41e-06

GO:0004017

Adenylate kinase activity

3 of 4

3.24

3.23

1.41e-06

GO:0016772

Transferase activity, transferring phosphorus-containing groups

7 of 765

1.32

1.68

2.39e-06

(more ...)

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:36277867

(2022) Cold-induced denaturation of muscle proteins in hairtail (Trichiurus lepturus) during storage: Physicochemical and label-free based proteomics analyses.

3 of 52

2.12

1.26

0.0040

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5678

Purine metabolism

9 of 40

2.72

9.69

3.16e-20

CL:5732

Mixed, incl. CTP metabolic process, and Adenylate kinase activity

7 of 13

3.09

9.1

9.18e-18

CL:5673

Mixed, incl. Purine metabolism, and Metabolism of nucleotides

10 of 157

2.17

7.13

1.42e-18

CL:5748

Adenylate kinase activity, and ATP cone domain

4 of 5

3.27

4.99

8.16e-10

CL:5734

Nucleoside diphosphate kinase, and Purine ribonucleoside bisphosphate metabolic process

2 of 5

2.97

1.63

0.0011

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pvm00230

Purine metabolism

9 of 76

2.44

8.5

2.35e-19

pvm00730

Thiamine metabolism

5 of 10

3.06

6.48

9.96e-13

pvm00240

Pyrimidine metabolism

5 of 36

2.51

5.02

1.24e-10

pvm00983

Drug metabolism - other enzymes

4 of 49

2.28

3.42

1.40e-07

pvm01100

Metabolic pathways

10 of 991

1.37

2.44

3.87e-12

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-499943

Interconversion of nucleotide di- and triphosphates

5 of 21

2.74

4.93

4.73e-10

MAP-15869

Metabolism of nucleotides

6 of 104

2.12

4.02

1.80e-09

MAP-1430728

Metabolism

7 of 2301

0.85

0.61

0.0055

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0418

Kinase

7 of 411

1.59

2.59

2.75e-08

KW-0547

Nucleotide-binding

6 of 685

1.31

1.48

2.31e-05

KW-0067

ATP-binding

5 of 552

1.32

1.33

0.00015

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13207

AAA domain

3 of 5

3.14

2.93

4.83e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR034907

Nucleoside diphosphate kinase-like domain

3 of 3

3.36

2.93

5.10e-06

IPR001564

Nucleoside diphosphate kinase

3 of 3

3.36

2.93

5.10e-06

IPR036850

Nucleoside diphosphate kinase-like domain superfamily

3 of 5

3.14

2.92

5.10e-06

IPR033690

Adenylate kinase, conserved site

3 of 5

3.14

2.92

5.10e-06

IPR000850

Adenylate kinase/UMP-CMP kinase

3 of 6

3.06

2.91

5.10e-06

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00562

These are enzymes that catalyze nonsubstrate specific conversions of nucleoside diphosphates to nucleoside triphosphates. These enzymes play important roles in bacterial growth, signal transduction and pathogenicity.

3 of 3

3.36

3.43

6.44e-07

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