A0A4S8JI65 protein (Musa balbisiana) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

A0A4S8JI65

Uncharacterized protein. (725 aa)

Predicted Functional Partners:

A0A4S8K4A0

0.729

A0A4S8J451

0.722

A0A4S8JQD3

0.722

A0A4S8K2J9

0.694

A0A4S8JL51

0.692

A0A4S8IZM7

0.672

A0A4S8KDZ8

0.672

A0A4V4HA26

0.672

A0A4S8JUX4

0.665

A0A4S8J319

0.661

Your Current Organism:

Musa balbisiana

NCBI taxonomy Id: 52838
Other names: Balbis banana, M. balbisiana, Musa BB Group, Musa balbisiana Colla, starchy banana

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A4S8IZM7	A0A4S8J319	CSD_1 domain-containing protein.	Nuclear cap-binding protein subunit 2.	0.755
A0A4S8IZM7	A0A4S8J451	CSD_1 domain-containing protein.	RRM domain-containing protein.	0.699
A0A4S8IZM7	A0A4S8JI65	CSD_1 domain-containing protein.	Uncharacterized protein.	0.672
A0A4S8IZM7	A0A4S8JL51	CSD_1 domain-containing protein.	SPRY domain-containing protein.	0.744
A0A4S8IZM7	A0A4S8JQD3	CSD_1 domain-containing protein.	Uncharacterized protein.	0.699
A0A4S8IZM7	A0A4S8JUX4	CSD_1 domain-containing protein.	MIF4G domain-containing protein.	0.753
A0A4S8IZM7	A0A4S8K2J9	CSD_1 domain-containing protein.	Uncharacterized protein.	0.808
A0A4S8IZM7	A0A4S8K4A0	CSD_1 domain-containing protein.	Uncharacterized protein.	0.752
A0A4S8J319	A0A4S8IZM7	Nuclear cap-binding protein subunit 2.	CSD_1 domain-containing protein.	0.755
A0A4S8J319	A0A4S8J451	Nuclear cap-binding protein subunit 2.	RRM domain-containing protein.	0.816
A0A4S8J319	A0A4S8JI65	Nuclear cap-binding protein subunit 2.	Uncharacterized protein.	0.661
A0A4S8J319	A0A4S8JL51	Nuclear cap-binding protein subunit 2.	SPRY domain-containing protein.	0.758
A0A4S8J319	A0A4S8JQD3	Nuclear cap-binding protein subunit 2.	Uncharacterized protein.	0.816
A0A4S8J319	A0A4S8JUX4	Nuclear cap-binding protein subunit 2.	MIF4G domain-containing protein.	0.997
A0A4S8J319	A0A4S8K2J9	Nuclear cap-binding protein subunit 2.	Uncharacterized protein.	0.951
A0A4S8J319	A0A4S8K4A0	Nuclear cap-binding protein subunit 2.	Uncharacterized protein.	0.758
A0A4S8J319	A0A4S8KDZ8	Nuclear cap-binding protein subunit 2.	CSD_1 domain-containing protein.	0.755
A0A4S8J319	A0A4V4HA26	Nuclear cap-binding protein subunit 2.	CSD_1 domain-containing protein.	0.755
A0A4S8J451	A0A4S8IZM7	RRM domain-containing protein.	CSD_1 domain-containing protein.	0.699
A0A4S8J451	A0A4S8J319	RRM domain-containing protein.	Nuclear cap-binding protein subunit 2.	0.816

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.842

expected number of edges:

11

PPI enrichment p-value:

4.46e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016579

Protein deubiquitination

3 of 46

2.57

2.88

0.00013

GO:0006511

Ubiquitin-dependent protein catabolic process

3 of 262

1.82

1.43

0.0069

GO:0036211

Protein modification process

4 of 1352

1.23

1.0

0.0069

GO:0044260

Cellular macromolecule metabolic process

4 of 1722

1.13

0.87

0.0091

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004843

Cysteine-type deubiquitinase activity

3 of 39

2.65

3.31

3.50e-05

GO:0003682

Chromatin binding

2 of 100

2.06

1.16

0.0257

GO:0140096

Catalytic activity, acting on a protein

4 of 1397

1.22

1.04

0.0042

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031519

PcG protein complex

2 of 3

3.58

2.92

0.00018

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2292

Proteasome complex

3 of 44

2.59

3.06

7.55e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5689603

UCH proteinases

4 of 187

2.09

3.39

4.29e-06

MAP-5688426

Deubiquitination

4 of 307

1.87

2.79

1.53e-05

MAP-597592

Post-translational protein modification

4 of 1244

1.27

1.14

0.0027

MAP-392499

Metabolism of proteins

4 of 1679

1.14

0.91

0.0067

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01088

Ubiquitin carboxyl-terminal hydrolase, family 1

3 of 6

3.46

5.21

1.88e-07

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036959

Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily

3 of 6

3.46

4.87

5.27e-07

IPR001578

Peptidase C12, ubiquitin carboxyl-terminal hydrolase

3 of 6

3.46

4.87

5.27e-07

IPR038765

Papain-like cysteine peptidase superfamily

3 of 64

2.43

2.9

0.00010

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