A0A4S8KFB5 protein (Musa balbisiana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A4S8KFB5

Uncharacterized protein. (301 aa)

Predicted Functional Partners:

A0A4S8JKV2

0.679

A0A4S8IX61

0.649

A0A4S8IQC4

0.631

A0A4S8J690

0.592

A0A4S8JTS4

0.592

A0A4S8KDS8

0.592

A0A4V4H5H0

0.592

A0A4S8IDD7

0.548

A0A4S8IGL8

0.548

A0A4S8IJ54

0.548

Your Current Organism:

Musa balbisiana

NCBI taxonomy Id: 52838
Other names: Balbis banana, M. balbisiana, Musa BB Group, Musa balbisiana Colla, starchy banana

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A4S8IDD7	A0A4S8IJ54	Glycerol-3-phosphate dehydrogenase [NAD(+)].	Uncharacterized protein.	0.822
A0A4S8IDD7	A0A4S8J690	Glycerol-3-phosphate dehydrogenase [NAD(+)].	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.913
A0A4S8IDD7	A0A4S8JTS4	Glycerol-3-phosphate dehydrogenase [NAD(+)].	PlsC domain-containing protein.	0.920
A0A4S8IDD7	A0A4S8KDS8	Glycerol-3-phosphate dehydrogenase [NAD(+)].	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.920
A0A4S8IDD7	A0A4S8KFB5	Glycerol-3-phosphate dehydrogenase [NAD(+)].	Uncharacterized protein.	0.548
A0A4S8IDD7	A0A4V4H5H0	Glycerol-3-phosphate dehydrogenase [NAD(+)].	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.913
A0A4S8IGL8	A0A4S8IQC4	Uncharacterized protein.	Uncharacterized protein.	0.932
A0A4S8IGL8	A0A4S8IX61	Uncharacterized protein.	Uncharacterized protein.	0.962
A0A4S8IGL8	A0A4S8KFB5	Uncharacterized protein.	Uncharacterized protein.	0.548
A0A4S8IJ54	A0A4S8IDD7	Uncharacterized protein.	Glycerol-3-phosphate dehydrogenase [NAD(+)].	0.822
A0A4S8IJ54	A0A4S8J690	Uncharacterized protein.	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.797
A0A4S8IJ54	A0A4S8JTS4	Uncharacterized protein.	PlsC domain-containing protein.	0.797
A0A4S8IJ54	A0A4S8KDS8	Uncharacterized protein.	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.797
A0A4S8IJ54	A0A4S8KFB5	Uncharacterized protein.	Uncharacterized protein.	0.548
A0A4S8IJ54	A0A4V4H5H0	Uncharacterized protein.	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.797
A0A4S8IQC4	A0A4S8IGL8	Uncharacterized protein.	Uncharacterized protein.	0.932
A0A4S8IQC4	A0A4S8KFB5	Uncharacterized protein.	Uncharacterized protein.	0.631
A0A4S8IX61	A0A4S8IGL8	Uncharacterized protein.	Uncharacterized protein.	0.962
A0A4S8IX61	A0A4S8KFB5	Uncharacterized protein.	Uncharacterized protein.	0.649
A0A4S8J690	A0A4S8IDD7	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	Glycerol-3-phosphate dehydrogenase [NAD(+)].	0.913

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.726

expected number of edges:

20

PPI enrichment p-value:

3.07e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1903438

Positive regulation of mitotic cytokinetic process

3 of 3

3.47

3.37

8.36e-07

GO:1901893

Positive regulation of cell septum assembly

3 of 3

3.47

3.37

8.36e-07

GO:0032955

Regulation of division septum assembly

3 of 6

3.16

3.31

9.85e-07

GO:0051247

Positive regulation of protein metabolic process

5 of 180

1.91

2.7

9.85e-07

GO:0031401

Positive regulation of protein modification process

4 of 91

2.11

2.58

5.60e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030295

Protein kinase activator activity

3 of 30

2.47

1.86

0.00034

GO:0004674

Protein serine/threonine kinase activity

5 of 993

1.17

0.95

0.0018

GO:0003924

GTPase activity

3 of 287

1.48

0.87

0.0134

GO:0035639

Purine ribonucleoside triphosphate binding

8 of 3305

0.85

0.71

0.00083

GO:0005525

GTP binding

3 of 387

1.35

0.71

0.0274

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0035838

Growing cell tip

2 of 10

2.77

1.23

0.0058

GO:0090406

Pollen tube

2 of 45

2.11

0.92

0.0188

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:24027

Mixed, incl. Extension to Ser/Thr-type protein kinases, and Signaling by Hippo

7 of 22

2.97

8.4

1.29e-16

CL:24017

Mixed, incl. Extension to Ser/Thr-type protein kinases, and Site of polarized growth

8 of 46

2.71

8.32

3.21e-17

CL:24049

Signaling by Hippo, and Extension to Ser/Thr-type protein kinases

4 of 11

3.03

4.38

8.89e-09

CL:24028

Mixed, incl. Regulation of mitotic cytokinesis, and TBC/RABGAPs

3 of 11

2.9

2.78

8.15e-06

CL:24051

Signaling by Hippo, and Extension to Ser/Thr-type protein kinases

2 of 6

2.99

1.49

0.0020

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03040

Spliceosome

3 of 382

1.36

0.65

0.0394

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-2028269

Signaling by Hippo

3 of 3

3.47

3.49

5.08e-07

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0034973

Sid2-Mob1 complex

3 of 3

3.47

3.38

8.04e-07

GOCC:0090404

Pollen tube tip

3 of 19

2.66

2.44

3.09e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF08477

Ras of Complex, Roc, domain of DAPkinase

3 of 6

3.16

2.91

5.29e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036703

MOB kinase activator superfamily

3 of 3

3.47

3.01

3.73e-06

IPR005301

MOB kinase activator family

3 of 3

3.47

3.01

3.73e-06

IPR017231

Small GTPase Tem1/Spg1

2 of 2

3.47

1.61

0.0013

IPR017892

Protein kinase, C-terminal

2 of 6

2.99

1.29

0.0047

IPR000961

AGC-kinase, C-terminal

2 of 13

2.65

1.05

0.0122

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01388

Mob1/phocein family

3 of 3

3.47

3.6

3.13e-07

SM00133

Extension to Ser/Thr-type protein kinases

2 of 8

2.86

1.59

0.0013

SM00220

Serine/Threonine protein kinases, catalytic domain

3 of 258

1.53

0.87

0.0145

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