STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BN2166_0074670Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (691 aa)    
Predicted Functional Partners:
BN2166_0022580
Autophagy-related protein.
   
 0.997
BN2166_0017480
Autophagy-related protein 3.
    
 0.996
BN2166_0029150
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
    
 0.994
BN2166_0054980
BY PROTMAP: gi|647394255|emb|CDR35483.1| RHTO0S01e00254g1_1 [Rhodosporidium toruloides].
  
 0.979
BN2166_0005610
annotation not available
   
 
 0.969
BN2166_0007910
FGENESH: predicted gene_1.791 protein.
    
 0.969
BN2166_0036130
annotation not available
    
 0.896
BN2166_0041490
Ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.879
BN2166_0054430
UBC-like protein.
    
 0.872
BN2166_0015490
FGENESH: predicted gene_2.718 protein.
  
 0.845
Your Current Organism:
Rhodotorula toruloides
NCBI taxonomy Id: 5286
Other names: CBS 6016, IFO 8766, IGC 5615, MUCL 28631, NRRL Y-6987, R. toruloides, Rhodosporidium toruloides, Rhodotorula gracilis, Rhodotorula rubescens, Rhodotorula toruloides (I. Banno) Q.M. Wang, F.Y. Bai, M. Groenew. & Boekhout, 2015
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.