node1 | node2 | node1 annotation | node2 annotation | score |
A0A5C5FNI2 | A0A5C5FPW1 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.675 |
A0A5C5FNI2 | A0A5C5FQR6 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.945 |
A0A5C5FNI2 | A0A5C5FRR0 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Thiolase, N-terminal domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.871 |
A0A5C5FNI2 | A0A5C5FRR3 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Acetyl-CoA carboxylase. | 0.782 |
A0A5C5FNI2 | A0A5C5FT49 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | HotDog domain-containing protein. | 0.761 |
A0A5C5FNI2 | A0A5C5FT51 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Putative electron transfer flavo protein alpha subunit. | 0.683 |
A0A5C5FNI2 | A0A5C5G2I5 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Acetyl-coenzyme A synthetase. | 0.882 |
A0A5C5FNI2 | A0A5C5G5X9 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.936 |
A0A5C5FNI2 | A0A5C5G630 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.592 |
A0A5C5FPW1 | A0A5C5FNI2 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.675 |
A0A5C5FPW1 | A0A5C5FQR6 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.804 |
A0A5C5FPW1 | A0A5C5FRR0 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Thiolase, N-terminal domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.736 |
A0A5C5FPW1 | A0A5C5FT49 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | HotDog domain-containing protein. | 0.759 |
A0A5C5FPW1 | A0A5C5G2I5 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Acetyl-coenzyme A synthetase. | 0.956 |
A0A5C5FPW1 | A0A5C5G5X9 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.668 |
A0A5C5FPW1 | A0A5C5G630 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.802 |
A0A5C5FQR6 | A0A5C5FNI2 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.945 |
A0A5C5FQR6 | A0A5C5FPW1 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.804 |
A0A5C5FQR6 | A0A5C5FRR0 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Thiolase, N-terminal domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.916 |
A0A5C5FQR6 | A0A5C5FRR3 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Acetyl-CoA carboxylase. | 0.769 |