STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C5FT49HotDog domain-containing protein. (534 aa)    
Predicted Functional Partners:
A0A5C5FRY1
Pre-mRNA splicing factor-domain-containing protein.
   
    0.806
A0A5C5G2I5
Acetyl-coenzyme A synthetase.
     
 0.788
A0A5C5FT51
Putative electron transfer flavo protein alpha subunit.
    
 0.777
A0A5C5FRR0
Thiolase, N-terminal domain-containing protein; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.775
A0A5C5G5X9
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
     
 0.771
A0A5C5FNI2
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
  0.761
A0A5C5FRR3
Acetyl-CoA carboxylase.
    
 0.760
A0A5C5FPW1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.759
A0A5C5G630
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.759
A0A5C5FQR6
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
  0.756
Your Current Organism:
Rhodotorula diobovata
NCBI taxonomy Id: 5288
Other names: ATCC 22265, CBS 6085, CCRC 22473, CCRC:22473, IGC 4364, JCM 3787, MUCL 30314, NCYC 2642, NRRL Y-7196, R. diobovata, Rhodosporidium diobovatum, Rhodotorula diobovata (S.Y. Newell & I.L. Hunter) Q.M. Wang, F.Y. Bai, M. Groenew. & Boekhout, 2015
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