node1 | node2 | node1 annotation | node2 annotation | score |
A0A5C5FMD4 | A0A5C5FRA7 | Phenylalanine ammonia-lyase. | Pyridoxal phosphate-dependent transferase. | 0.936 |
A0A5C5FMD4 | A0A5C5FX42 | Phenylalanine ammonia-lyase. | Phosphoribosyl-ATP pyrophosphatase. | 0.768 |
A0A5C5FMD4 | A0A5C5FX53 | Phenylalanine ammonia-lyase. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.594 |
A0A5C5FMD4 | A0A5C5FX96 | Phenylalanine ammonia-lyase. | Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.810 |
A0A5C5FMD4 | A0A5C5FXT5 | Phenylalanine ammonia-lyase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.856 |
A0A5C5FMD4 | A0A5C5G203 | Phenylalanine ammonia-lyase. | Uncharacterized protein. | 0.542 |
A0A5C5FNT7 | A0A5C5FRA7 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Pyridoxal phosphate-dependent transferase. | 0.995 |
A0A5C5FNT7 | A0A5C5FWV1 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Tryptophan synthase. | 0.774 |
A0A5C5FNT7 | A0A5C5FX42 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Phosphoribosyl-ATP pyrophosphatase. | 0.996 |
A0A5C5FNT7 | A0A5C5FX53 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.997 |
A0A5C5FNT7 | A0A5C5FX96 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.997 |
A0A5C5FNT7 | A0A5C5FXT5 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.982 |
A0A5C5FNT7 | A0A5C5FYW5 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | tRNA_lig_kinase domain-containing protein. | 0.882 |
A0A5C5FNT7 | A0A5C5G114 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.656 |
A0A5C5FNT7 | A0A5C5G203 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Uncharacterized protein. | 0.995 |
A0A5C5FRA7 | A0A5C5FMD4 | Pyridoxal phosphate-dependent transferase. | Phenylalanine ammonia-lyase. | 0.936 |
A0A5C5FRA7 | A0A5C5FNT7 | Pyridoxal phosphate-dependent transferase. | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 0.995 |
A0A5C5FRA7 | A0A5C5FWV1 | Pyridoxal phosphate-dependent transferase. | Tryptophan synthase. | 0.989 |
A0A5C5FRA7 | A0A5C5FX42 | Pyridoxal phosphate-dependent transferase. | Phosphoribosyl-ATP pyrophosphatase. | 0.983 |
A0A5C5FRA7 | A0A5C5FX53 | Pyridoxal phosphate-dependent transferase. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.976 |