STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
A0A5C5G5M22-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (479 aa)    
Predicted Functional Partners:
A0A5C5G274
Thiamine diphosphate-binding protein.
 0.999
A0A5C5G685
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
A0A5C5FZI5
Dihydrolipoyl dehydrogenase.
  
 
 0.959
A0A5C5FJ85
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.931
A0A5C5FTC8
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.931
A0A5C5FJU3
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.930
A0A5C5FMI4
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.930
A0A5C5G298
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 
 0.924
A0A5C5FNI2
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.922
A0A5C5G3B7
Lipoyl-binding domain-containing protein.
  
 0.895
Your Current Organism:
Rhodotorula diobovata
NCBI taxonomy Id: 5288
Other names: ATCC 22265, CBS 6085, CCRC 22473, CCRC:22473, IGC 4364, JCM 3787, MUCL 30314, NCYC 2642, NRRL Y-7196, R. diobovata, Rhodosporidium diobovatum, Rhodotorula diobovata (S.Y. Newell & I.L. Hunter) Q.M. Wang, F.Y. Bai, M. Groenew. & Boekhout, 2015
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