STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSMAP00000001033RAD18 E3 ubiquitin protein ligase. (499 aa)    
Predicted Functional Partners:
SMAX5B_010392
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.997
SMAX5B_021975
Putative helicase-like transcription factor.
   
 0.986
SMAX5B_004313
Ubiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.969
ENSSMAP00000020813
Ubiquitin-conjugating enzyme E2A (RAD6 homolog).
    
 0.969
SMAX5B_022127
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 
 0.969
SMAX5B_018306
Putative ubiquitin-conjugating enzyme E2 A isoform 3; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.969
SMAX5B_000328
Putative Fanconi anemia group M protein.
   
 
 0.968
ENSSMAP00000008002
Ribosomal protein S27a.
    
 0.961
SMAX5B_001274
Putative DNA polymerase zeta catalytic subunit.
   
 0.953
ENSSMAP00000034351
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.948
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.