| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSSMAP00000015865 | SMAX5B_008821 | ENSSMAP00000015865 | ENSSMAP00000006334 | Glutamate-cysteine ligase, modifier subunit. | Putative 5-phosphohydroxy-L-lysine phospho-lyase isoform 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.518 |
| ENSSMAP00000015865 | SMAX5B_012704 | ENSSMAP00000015865 | ENSSMAP00000001160 | Glutamate-cysteine ligase, modifier subunit. | Aspartate aminotransferase. | 0.864 |
| ENSSMAP00000015865 | SMAX5B_016624 | ENSSMAP00000015865 | ENSSMAP00000018529 | Glutamate-cysteine ligase, modifier subunit. | Putative ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.518 |
| ENSSMAP00000015865 | SMAX5B_022661 | ENSSMAP00000015865 | ENSSMAP00000001884 | Glutamate-cysteine ligase, modifier subunit. | Putative hydroxylysine kinase. | 0.879 |
| ENSSMAP00000015865 | SMAX5B_022673 | ENSSMAP00000015865 | ENSSMAP00000004400 | Glutamate-cysteine ligase, modifier subunit. | Putative cystathionine gamma-lyase isoform 2. | 0.881 |
| KMO | KYNU | ENSSMAP00000022564 | ENSSMAP00000021840 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.995 |
| KMO | SMAX5B_013122 | ENSSMAP00000022564 | ENSSMAP00000018395 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Bifunctional glutamate/proline--tRNA ligase. | 0.430 |
| KMO | SMAX5B_021114 | ENSSMAP00000022564 | ENSSMAP00000023186 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Putative kynurenine/alpha-aminoadipate aminotransferase mitochondrial. | 0.931 |
| KMO | SMAX5B_022661 | ENSSMAP00000022564 | ENSSMAP00000001884 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Putative hydroxylysine kinase. | 0.881 |
| KMO | SMAX5B_022673 | ENSSMAP00000022564 | ENSSMAP00000004400 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Putative cystathionine gamma-lyase isoform 2. | 0.416 |
| KYNU | KMO | ENSSMAP00000021840 | ENSSMAP00000022564 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.995 |
| KYNU | SMAX5B_021114 | ENSSMAP00000021840 | ENSSMAP00000023186 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | Putative kynurenine/alpha-aminoadipate aminotransferase mitochondrial. | 0.925 |
| KYNU | SMAX5B_022661 | ENSSMAP00000021840 | ENSSMAP00000001884 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | Putative hydroxylysine kinase. | 0.880 |
| SMAX5B_008821 | ENSSMAP00000015865 | ENSSMAP00000006334 | ENSSMAP00000015865 | Putative 5-phosphohydroxy-L-lysine phospho-lyase isoform 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate-cysteine ligase, modifier subunit. | 0.518 |
| SMAX5B_008821 | SMAX5B_013122 | ENSSMAP00000006334 | ENSSMAP00000018395 | Putative 5-phosphohydroxy-L-lysine phospho-lyase isoform 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Bifunctional glutamate/proline--tRNA ligase. | 0.544 |
| SMAX5B_008821 | SMAX5B_021114 | ENSSMAP00000006334 | ENSSMAP00000023186 | Putative 5-phosphohydroxy-L-lysine phospho-lyase isoform 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Putative kynurenine/alpha-aminoadipate aminotransferase mitochondrial. | 0.467 |
| SMAX5B_008821 | SMAX5B_022661 | ENSSMAP00000006334 | ENSSMAP00000001884 | Putative 5-phosphohydroxy-L-lysine phospho-lyase isoform 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Putative hydroxylysine kinase. | 0.969 |
| SMAX5B_008821 | SMAX5B_022673 | ENSSMAP00000006334 | ENSSMAP00000004400 | Putative 5-phosphohydroxy-L-lysine phospho-lyase isoform 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Putative cystathionine gamma-lyase isoform 2. | 0.837 |
| SMAX5B_012704 | ENSSMAP00000015865 | ENSSMAP00000001160 | ENSSMAP00000015865 | Aspartate aminotransferase. | Glutamate-cysteine ligase, modifier subunit. | 0.864 |
| SMAX5B_012704 | SMAX5B_016008 | ENSSMAP00000001160 | ENSSMAP00000022625 | Aspartate aminotransferase. | Putative 1-2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene); Belongs to the acireductone dioxygenase (ARD) family. | 0.804 |