SMAX5B_015982 protein (Scophthalmus maximus)

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Score

SMAX5B_015982

Small ubiquitin-related modifier. (101 aa)

Predicted Functional Partners:

SMAX5B_015371

0.999

SMAX5B_018361

0.996

SMAX5B_019975

0.993

SMAX5B_005752

0.992

ENSSMAP00000020441

0.992

SMAX5B_015688

0.988

SMAX5B_022595

0.985

SMAX5B_001446

0.983

SMAX5B_020527

0.981

SMAX5B_006685

0.978

Your Current Organism:

Scophthalmus maximus

NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSMAP00000020441	SMAX5B_001446	ENSSMAP00000020441	ENSSMAP00000015064	Ubiquitin-conjugating enzyme E2Ia.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.913
ENSSMAP00000020441	SMAX5B_005752	ENSSMAP00000020441	ENSSMAP00000012316	Ubiquitin-conjugating enzyme E2Ia.	Putative SUMO-conjugating enzyme UBC9 isoform 3; Belongs to the ubiquitin-conjugating enzyme family.	0.843
ENSSMAP00000020441	SMAX5B_006685	ENSSMAP00000020441	ENSSMAP00000009599	Ubiquitin-conjugating enzyme E2Ia.	Putative ran GTPase-activating protein 1.	0.961
ENSSMAP00000020441	SMAX5B_015371	ENSSMAP00000020441	ENSSMAP00000025763	Ubiquitin-conjugating enzyme E2Ia.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.980
ENSSMAP00000020441	SMAX5B_015688	ENSSMAP00000020441	ENSSMAP00000028503	Ubiquitin-conjugating enzyme E2Ia.	Putative death domain-associated protein 6.	0.856
ENSSMAP00000020441	SMAX5B_015982	ENSSMAP00000020441	ENSSMAP00000002013	Ubiquitin-conjugating enzyme E2Ia.	Small ubiquitin-related modifier.	0.992
ENSSMAP00000020441	SMAX5B_018361	ENSSMAP00000020441	ENSSMAP00000011896	Ubiquitin-conjugating enzyme E2Ia.	Putative E3 SUMO-protein ligase RanBP2.	0.998
ENSSMAP00000020441	SMAX5B_019975	ENSSMAP00000020441	ENSSMAP00000032154	Ubiquitin-conjugating enzyme E2Ia.	Putative SUMO-activating enzyme subunit 1 isoform 3.	0.972
ENSSMAP00000020441	SMAX5B_022595	ENSSMAP00000020441	ENSSMAP00000018059	Ubiquitin-conjugating enzyme E2Ia.	E3 SUMO-protein ligase PIAS4.	0.933
SMAX5B_001446	ENSSMAP00000020441	ENSSMAP00000015064	ENSSMAP00000020441	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ubiquitin-conjugating enzyme E2Ia.	0.913
SMAX5B_001446	SMAX5B_005752	ENSSMAP00000015064	ENSSMAP00000012316	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Putative SUMO-conjugating enzyme UBC9 isoform 3; Belongs to the ubiquitin-conjugating enzyme family.	0.913
SMAX5B_001446	SMAX5B_015688	ENSSMAP00000015064	ENSSMAP00000028503	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Putative death domain-associated protein 6.	0.990
SMAX5B_001446	SMAX5B_015982	ENSSMAP00000015064	ENSSMAP00000002013	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Small ubiquitin-related modifier.	0.983
SMAX5B_001446	SMAX5B_018361	ENSSMAP00000015064	ENSSMAP00000011896	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Putative E3 SUMO-protein ligase RanBP2.	0.523
SMAX5B_001446	SMAX5B_020527	ENSSMAP00000015064	ENSSMAP00000016318	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	BTB/POZ domain-containing protein KCTD2.	0.802
SMAX5B_001446	SMAX5B_022595	ENSSMAP00000015064	ENSSMAP00000018059	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	E3 SUMO-protein ligase PIAS4.	0.924
SMAX5B_005752	ENSSMAP00000020441	ENSSMAP00000012316	ENSSMAP00000020441	Putative SUMO-conjugating enzyme UBC9 isoform 3; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2Ia.	0.843
SMAX5B_005752	SMAX5B_001446	ENSSMAP00000012316	ENSSMAP00000015064	Putative SUMO-conjugating enzyme UBC9 isoform 3; Belongs to the ubiquitin-conjugating enzyme family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.913
SMAX5B_005752	SMAX5B_006685	ENSSMAP00000012316	ENSSMAP00000009599	Putative SUMO-conjugating enzyme UBC9 isoform 3; Belongs to the ubiquitin-conjugating enzyme family.	Putative ran GTPase-activating protein 1.	0.960
SMAX5B_005752	SMAX5B_015371	ENSSMAP00000012316	ENSSMAP00000025763	Putative SUMO-conjugating enzyme UBC9 isoform 3; Belongs to the ubiquitin-conjugating enzyme family.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.980