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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_001553Putative DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3875 aa)    
Predicted Functional Partners:
SMAX5B_018474
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
   
 0.994
SMAX5B_020350
Putative X-ray repair cross-complementing protein 6.
    
 0.993
SMAX5B_008033
DRMBL domain-containing protein.
    
 0.991
SMAX5B_001446
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.985
SMAX5B_001923
Putative regulatory-associated protein of mTOR.
   
 0.984
SMAX5B_010883
Putative rapamycin-insensitive companion of mTOR-like.
   
 0.983
ENSSMAP00000014343
MTOR associated protein, LST8 homolog (S. cerevisiae).
    
 0.982
SMAX5B_004116
Ras-related GTP binding A isoform 2.
    
 0.980
SMAX5B_022695
DNA ligase.
   
 0.979
SMAX5B_002662
Putative TELO2-interacting protein 1-like.
   
 0.978
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.