| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSSMAP00000001909 | FEN1 | ENSSMAP00000001909 | ENSSMAP00000032702 | Poly (ADP-ribose) glycohydrolase a. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.643 |
| ENSSMAP00000001909 | SMAX5B_006294 | ENSSMAP00000001909 | ENSSMAP00000012032 | Poly (ADP-ribose) glycohydrolase a. | Putative flap endonuclease 1-like. | 0.643 |
| ENSSMAP00000001909 | SMAX5B_006687 | ENSSMAP00000001909 | ENSSMAP00000002265 | Poly (ADP-ribose) glycohydrolase a. | Putative von Willebrand factor A domain-containing protein 5B2. | 0.847 |
| ENSSMAP00000001909 | SMAX5B_020350 | ENSSMAP00000001909 | ENSSMAP00000010534 | Poly (ADP-ribose) glycohydrolase a. | Putative X-ray repair cross-complementing protein 6. | 0.426 |
| FEN1 | ENSSMAP00000001909 | ENSSMAP00000032702 | ENSSMAP00000001909 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Poly (ADP-ribose) glycohydrolase a. | 0.643 |
| FEN1 | SMAX5B_002752 | ENSSMAP00000032702 | ENSSMAP00000016723 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Putative DNA repair protein complementing XP-C cells. | 0.696 |
| FEN1 | SMAX5B_006294 | ENSSMAP00000032702 | ENSSMAP00000012032 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Putative flap endonuclease 1-like. | 0.851 |
| FEN1 | SMAX5B_006687 | ENSSMAP00000032702 | ENSSMAP00000002265 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Putative von Willebrand factor A domain-containing protein 5B2. | 0.723 |
| FEN1 | SMAX5B_017274 | ENSSMAP00000032702 | ENSSMAP00000004217 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Putative poly(ADP-ribose) glycohydrolase-like. | 0.643 |
| FEN1 | SMAX5B_018474 | ENSSMAP00000032702 | ENSSMAP00000016793 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. | 0.686 |
| FEN1 | SMAX5B_020350 | ENSSMAP00000032702 | ENSSMAP00000010534 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Putative X-ray repair cross-complementing protein 6. | 0.772 |
| SMAX5B_002752 | FEN1 | ENSSMAP00000016723 | ENSSMAP00000032702 | Putative DNA repair protein complementing XP-C cells. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.696 |
| SMAX5B_002752 | SMAX5B_003989 | ENSSMAP00000016723 | ENSSMAP00000012049 | Putative DNA repair protein complementing XP-C cells. | H2AFY MGC137823 isoform 3; Belongs to the histone H2A family. | 0.416 |
| SMAX5B_002752 | SMAX5B_006294 | ENSSMAP00000016723 | ENSSMAP00000012032 | Putative DNA repair protein complementing XP-C cells. | Putative flap endonuclease 1-like. | 0.696 |
| SMAX5B_002752 | SMAX5B_006687 | ENSSMAP00000016723 | ENSSMAP00000002265 | Putative DNA repair protein complementing XP-C cells. | Putative von Willebrand factor A domain-containing protein 5B2. | 0.772 |
| SMAX5B_002752 | SMAX5B_008496 | ENSSMAP00000016723 | ENSSMAP00000026848 | Putative DNA repair protein complementing XP-C cells. | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | 0.416 |
| SMAX5B_002752 | SMAX5B_018474 | ENSSMAP00000016723 | ENSSMAP00000016793 | Putative DNA repair protein complementing XP-C cells. | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. | 0.616 |
| SMAX5B_002752 | SMAX5B_020350 | ENSSMAP00000016723 | ENSSMAP00000010534 | Putative DNA repair protein complementing XP-C cells. | Putative X-ray repair cross-complementing protein 6. | 0.675 |
| SMAX5B_003989 | SMAX5B_002752 | ENSSMAP00000012049 | ENSSMAP00000016723 | H2AFY MGC137823 isoform 3; Belongs to the histone H2A family. | Putative DNA repair protein complementing XP-C cells. | 0.416 |
| SMAX5B_003989 | SMAX5B_006687 | ENSSMAP00000012049 | ENSSMAP00000002265 | H2AFY MGC137823 isoform 3; Belongs to the histone H2A family. | Putative von Willebrand factor A domain-containing protein 5B2. | 0.705 |