| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH18A1 | SMAX5B_000321 | ENSSMAP00000018890 | ENSSMAP00000011530 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | C-1-tetrahydrofolate synthase cytoplasmic isoform 2. | 0.841 |
| ALDH18A1 | SMAX5B_005711 | ENSSMAP00000018890 | ENSSMAP00000029315 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Dihydrofolate reductase isoform 3. | 0.707 |
| ALDH18A1 | SMAX5B_006832 | ENSSMAP00000018890 | ENSSMAP00000024879 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.751 |
| ALDH18A1 | SMAX5B_011259 | ENSSMAP00000018890 | ENSSMAP00000002328 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | 0.923 |
| ALDH18A1 | SMAX5B_012789 | ENSSMAP00000018890 | ENSSMAP00000016461 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Putative dihydrofolate reductase-like. | 0.707 |
| ALDH18A1 | SMAX5B_013122 | ENSSMAP00000018890 | ENSSMAP00000018395 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Bifunctional glutamate/proline--tRNA ligase. | 0.848 |
| ALDH18A1 | SMAX5B_016696 | ENSSMAP00000018890 | ENSSMAP00000032515 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.551 |
| ALDH18A1 | SMAX5B_017306 | ENSSMAP00000018890 | ENSSMAP00000032972 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.998 |
| SMAX5B_000321 | ALDH18A1 | ENSSMAP00000011530 | ENSSMAP00000018890 | C-1-tetrahydrofolate synthase cytoplasmic isoform 2. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.841 |
| SMAX5B_000321 | SMAX5B_002747 | ENSSMAP00000011530 | ENSSMAP00000017617 | C-1-tetrahydrofolate synthase cytoplasmic isoform 2. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.941 |
| SMAX5B_000321 | SMAX5B_005711 | ENSSMAP00000011530 | ENSSMAP00000029315 | C-1-tetrahydrofolate synthase cytoplasmic isoform 2. | Dihydrofolate reductase isoform 3. | 0.915 |
| SMAX5B_000321 | SMAX5B_006832 | ENSSMAP00000011530 | ENSSMAP00000024879 | C-1-tetrahydrofolate synthase cytoplasmic isoform 2. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.997 |
| SMAX5B_000321 | SMAX5B_011259 | ENSSMAP00000011530 | ENSSMAP00000002328 | C-1-tetrahydrofolate synthase cytoplasmic isoform 2. | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | 0.893 |
| SMAX5B_000321 | SMAX5B_012789 | ENSSMAP00000011530 | ENSSMAP00000016461 | C-1-tetrahydrofolate synthase cytoplasmic isoform 2. | Putative dihydrofolate reductase-like. | 0.912 |
| SMAX5B_000321 | SMAX5B_016696 | ENSSMAP00000011530 | ENSSMAP00000032515 | C-1-tetrahydrofolate synthase cytoplasmic isoform 2. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.909 |
| SMAX5B_000321 | SMAX5B_017306 | ENSSMAP00000011530 | ENSSMAP00000032972 | C-1-tetrahydrofolate synthase cytoplasmic isoform 2. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.841 |
| SMAX5B_002747 | SMAX5B_000321 | ENSSMAP00000017617 | ENSSMAP00000011530 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | C-1-tetrahydrofolate synthase cytoplasmic isoform 2. | 0.941 |
| SMAX5B_002747 | SMAX5B_005711 | ENSSMAP00000017617 | ENSSMAP00000029315 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Dihydrofolate reductase isoform 3. | 0.890 |
| SMAX5B_002747 | SMAX5B_006832 | ENSSMAP00000017617 | ENSSMAP00000024879 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.962 |
| SMAX5B_002747 | SMAX5B_011259 | ENSSMAP00000017617 | ENSSMAP00000002328 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | 0.904 |