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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRMT5tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (477 aa)    
Predicted Functional Partners:
SMAX5B_009369
TRM112-like protein.
   
 
 0.903
SMAX5B_016467
Putative riboflavin kinase.
     
 0.902
SMAX5B_001305
Putative tRNA wybutosine-synthesizing protein 3-like.
  
 
 0.819
SMAX5B_019908
Putative S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase isoform 2.
  
 
 0.781
METTL1
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
   
  
 0.695
SMAX5B_011668
Putative FAD synthase isoform 3.
    
 0.677
SMAX5B_003961
Splicing factor 3B subunit 3.
   
 
  0.676
ENSSMAP00000001009
Dihydrouridine synthase 2.
   
  
 0.663
SMAX5B_008328
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
   
  
 0.658
SMAX5B_016190
Putative tRNA dimethylallyltransferase mitochondrial; Belongs to the IPP transferase family.
   
  
 0.658
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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