Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSSMAP000000027905-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (468 aa)    
Predicted Functional Partners:
SMAX5B_004764
Putative 5-hydroxytryptamine receptor 2A.
  
0.982
SMAX5B_007074
Putative 5-hydroxytryptamine receptor 2C-like.
    
 
0.961
SMAX5B_022424
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.959
SMAX5B_021945
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.959
SMAX5B_016552
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.959
SMAX5B_013856
Putative guanine nucleotide-binding protein G(Q) subunit alpha-like.
    
  0.926
SMAX5B_016471
Putative guanine nucleotide-binding protein subunit alpha-14-like.
    
 0.860
SMAX5B_022284
Putative guanine nucleotide-binding protein subunit alpha-11-like.
    
  0.778
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
  0.649
SMAX5B_009137
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
  0.649
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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