STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSMAP00000003252Methionine adenosyltransferase I, alpha. (400 aa)    
Predicted Functional Partners:
SMAX5B_021553
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
   
 0.965
SMAX5B_000518
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.954
ENSSMAP00000000642
Tyrosine aminotransferase.
  
 0.891
SMAX5B_007918
Putative homocysteine S-methyltransferase 1-like.
  
 
 0.887
SMAX5B_001310
S-adenosylmethionine decarboxylase proenzyme.
   
 
 0.883
SMAX5B_016696
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.876
SMAX5B_022673
Putative cystathionine gamma-lyase isoform 2.
  
 0.874
SMAX5B_002043
Putative tRNA (Cytosine(38)-C(5))-methyltransferase-like isoform 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.846
ENSSMAP00000013526
annotation not available
  
 0.843
SMAX5B_008392
Amine oxidase.
   
 0.839
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.