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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSMAP00000003422annotation not available (313 aa)    
Predicted Functional Partners:
ENSSMAP00000000568
Phospholipase C, gamma 2.
    
 0.886
SMAX5B_014655
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.886
SMAX5B_009222
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.886
VAV1
Putative proto-oncogene vav.
   
 0.754
SMAX5B_012259
Putative lymphocyte cytosolic protein 2-like.
   
 0.754
SMAX5B_009384
Putative cytokine-dependent hematopoietic cell linker-like.
   
 0.754
SMAX5B_006667
Putative guanine nucleotide exchange factor VAV3-like.
   
 0.754
SMAX5B_008509
Putative B-cell linker protein.
   
 0.754
SMAX5B_015192
Putative guanine nucleotide exchange factor VAV2.
   
 0.754
VAV3
Putative guanine nucleotide exchange factor VAV3-like.
   
 0.754
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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